Hydroxyamine hydrochloride → HCID 58043580, compound

Participants

Reaction Steps

In analogy to example 151, step 3, {3-fluoro-4-[3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-phenoxy}-acetic acid was reacted with hydroxylamine hydrochloride in the presence of NaHCO3 to give the title compound containing less than 10% of the corresponding Z isomer as a light brown solid, MS (ESI+): m/z=439.2 [M+H]+.

Provenance & Evidence