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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617745Generated: November 1, 2026

Hydrochloric Acid → HCID 66668752, compound

https://huagongshe.com/reaction/1617745

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant3-(4-Bromophenyl)-3-(4-chloro-2-methylphenyl)-1-(6-methoxypyridin-3-yl)propan-1-oneHCID 67015717—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66668752HCID 66668752—

Reaction Steps

In analogy to example 162, step 2, 3-(4-bromophenyl)-3-(4-chloro-2-methylphenyl)-1-(6-methoxypyridin-3-yl)propan-1-one was reacted with concentrated aqueous HCl in 1,4-dioxane to give the title compound as a colorless solid, MS (ESI+)=432,019 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-9bb8258a6d294e59a2095510b15931f4
Source noteuspto-grants-2014_07