Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617747Generated: November 2, 2026

Hydroxyamine hydrochloride → HCID 58043472, compound

https://huagongshe.com/reaction/1617747

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyamine hydrochlorideHCID 443297—
ReactantSodium BicarbonateHCID 516892—
ReactantHCID 66668381HCID 66668381—
ProductHCID 58043472HCID 58043472—

Reaction Steps

In analogy to example 151, step 3, 5-(3-(4-bromophenyl)-3-(4-chloro-2-methylphenyl)propanoyl)-1-methylpyridin-2(1H)-one was reacted with hydroxylamine hydrochloride in the presence of NaHCO3 to give the title compound containing 10% of the corresponding Z isomer as a colorless foam, MS (ESI+): m/z=461.05 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-e23a8dc28ba046ef82664575087a977a
Source noteuspto-grants-2014_07