Hydroxyamine hydrochloride → HCID 178480261, compound

Participants

Reaction Steps

In analogy to example 151, step 3, trans-4-{4-[1-(2-chloro-phenyl)-3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-propyl]-2-fluoro-benzoylamino}-cyclohexanecarboxylic acid was reacted with hydroxylamine hydrochloride in the presence of NaHCO3 to give the title compound containing 13% of the corresponding Z isomer as a colorless solid, MS (ESI+): m/z=552.3 [M+H]+.

Provenance & Evidence