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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617755Generated: November 2, 2026

Hydroxyamine hydrochloride → HCID 87098080, compound

https://huagongshe.com/reaction/1617755

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyamine hydrochlorideHCID 443297—
ReactantSodium BicarbonateHCID 516892—
ReactantHCID 67015655HCID 67015655—
ProductHCID 87098080HCID 87098080—

Reaction Steps

In analogy to example 151, step 3, 4-(1-(2-chlorophenyl)-3-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-3-oxopropyl)-N-cyclopropyl-2-fluorobenzamide was reacted with hydroxylamine hydrochloride in the presence of NaHCO3 to give the title compound containing 4% of the corresponding Z isomer as a colorless waxy solid, MS (ESI+): m/z=468.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-435045bf88b040818522997bf7177195
Source noteuspto-grants-2014_07