HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-aminoethyl)acetamide → HCID 67015600, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-aminoethyl)acetamide | HCID 66082 | — |
| Reactant | Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate | HCID 151348 | — |
| Reactant | 4-[3-(1-Methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-benzoic acid | HCID 67015525 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67015600 | HCID 67015600 | — |
Reaction Steps
In analogy to example 207, step 2, 4-[3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-benzoic acid (example 207, step 1) was coupled with N acetylethylenediamine using BOP reagent in tetrahydrofuran to give the title compound as an off-white solid, MS (ESI+): m/z=460.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-accc4b9b349a4c61bed2e8c02374bb6f |
| Source note | uspto-grants-2014_07 |