HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyamine hydrochloride → (NE)-N-[(4R)-4-(4-bromophenyl)-4-(2-methylphenyl)-1-pyridin-2-ylbutan-2-ylidene]hydroxylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | (R)-4-(4-Bromophenyl)-1-(pyridin-2-yl)-4-o-tolylbutan-2-one | HCID 67015648 | — |
| Product | (NE)-N-[(4R)-4-(4-bromophenyl)-4-(2-methylphenyl)-1-pyridin-2-ylbutan-2-ylidene]hydroxylamine | HCID 58043626 | — |
Reaction Steps
In analogy to example 74, step 7, from (R)-4-(4-bromophenyl)-1-(pyridin-2-yl)-4-o-tolylbutan-2-one and hydroxylamine hydrochloride in the presence of NaHCO3 was prepared the title compound as a colorless oil, MS (ESI+): m/z=409.0904 ([M+H]+, 1Br).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-2c02c6b1167c4b06bdad626cbc0242a3 |
| Source note | uspto-grants-2014_07 |