HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyamine hydrochloride → (NZ)-N-[(4R)-4-(4-bromophenyl)-4-(2-methylphenyl)-1-pyridin-4-ylbutan-2-ylidene]hydroxylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | (R)-4-(4-bromophenyl)-1-(pyridin-4-yl)-4-o-tolylbutan-2-one | HCID 66666163 | — |
| Product | (NZ)-N-[(4R)-4-(4-bromophenyl)-4-(2-methylphenyl)-1-pyridin-4-ylbutan-2-ylidene]hydroxylamine | HCID 58043446 | — |
Reaction Steps
In analogy to example 1, step 2, from (R)-4-(4-bromo-phenyl)-1-pyridin-4-yl-4-o-tolyl-butan-2-one and hydroxylamine hydrochloride in the presence of sodium hydrogencarbonate was prepared the title compound as a colourless oil, MS (ESI+): m/z=409.1 ([M+H]+, 1Br).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-3867f275f74b4efaabbbad23800a28b2 |
| Source note | uspto-grants-2014_07 |