Hydroxyamine hydrochloride → HCID 58043574, compound

Participants

Reaction Steps

In analogy to example 151, step 3, N-(1-hydroxy-2-methylpropan-2-yl)-4-(3-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-3-oxo-1-o-tolylpropyl)benzamide was reacted with hydroxylamine hydrochloride in the presence of sodium hydrogencarbonate to give the title compound as an off-white solid containing <10% of the corresponding Z isomer, MS (ESI+): m/z=462.3 [M+H]+.

Provenance & Evidence