HuagongsheHuagongshe Chemistry Print Report · For research reference only
Serinol → HCID 66668799, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Serinol | HCID 68294 | — |
| Reactant | Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate | HCID 151348 | — |
| Reactant | 4-[3-(1-Methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-benzoic acid | HCID 67015525 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 66668799 | HCID 66668799 | — |
Reaction Steps
In analogy to example 207, step 2, 4-[3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-1-o-tolyl-propyl]-benzoic acid (example 207, step 1) was coupled with 2-aminopropane-1,3-diol using benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate in tetrahydrofuran to give the title compound as an off-white solid, MS (ESI+): m/z=449.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765730B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-be68be13f96443f390abad30b247b07e |
| Source note | uspto-grants-2014_07 |