2-Amino-5-m-tolyl-thiazole-4-carboxylic acid → N-[[2-[2-amino-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-6-methylimidazo[2,1-b][1,3]thiazole-5-carboxamide

HRID 161789Notes

Reaction equation

HRID 161789 reaction equation
[CH:1]12[NH:2][CH:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]3[c:12]([CH3:19])[n:13][c:14]4[s:15][cH:16][cH:17][n:18]34)[CH2:4][CH:5]1[CH2:6]2.[NH2:20][c:21]1[s:22][c:23](-[c:29]2[cH:30][c:31]([CH3:35])[cH:32][cH:33][cH:34]2)[c:24]([C:26](=[O:27])[OH:28])[n:25]1>>[CH:1]12[N:2]([C:26]([c:24]3[c:23](-[c:29]4[cH:30][c:31]([CH3:35])[cH:32][cH:33][cH:34]4)[s:22][c:21]([NH2:20])[n:25]3)=[O:27])[CH:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]3[c:12]([CH3:19])[n:13][c:14]4[s:15][cH:16][cH:17][n:18]34)[CH2:4][CH:5]1[CH2:6]2

Participants

3

Reactant 2

HCID 532717422-Amino-5-m-tolyl-thiazole-4-carboxylic acidHCID 178432435HCID 178432435, compound

Product 1

HCID 74380271N-[[2-[2-amino-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-6-methylimidazo[2,1-b][1,3]thiazole-5-carboxamide

Sources & evidence

ORD record
ord-0692f54cc30f4a3eb6d56213841ce101
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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