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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1617899Generated: October 30, 2026

Hydroxyamine hydrochloride → HCID 58043350, compound

https://huagongshe.com/reaction/1617899

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyamine hydrochlorideHCID 443297—
ReactantSodium BicarbonateHCID 516892—
ReactantHCID 86661141HCID 86661141—
ProductHCID 58043350HCID 58043350—

Reaction Steps

In analogy to example 151, step 3, methanesulfonic acid 4-[1-(4-chloro-2-methyl-phenyl)-3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-propyl]-2-fluoro-phenyl ester was reacted with hydroxylamine hydrochloride in the presence of sodium hydrogencarbonate to give the title compound as a colourless solid, MS (ESI+): m/z=493.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08765730B2
Source datasetuspto-grants-2014_07
ORD IDord-307460f9e3fe4b539ad421f53d897407
Source noteuspto-grants-2014_07