Potassium Hydroxide → HCID 66667367, compound

HRID 1617900Notes

Reaction equation

HRID 1617900 reaction equation
[C:1]([C:4]1[CH:5]=[CH:6][C:7]([O:10][CH3:11])=[N:8][CH:9]=1)(=[O:3])[CH3:2].[CH3:12][C:13]1[N:14]=[CH:15][S:16][C:17]=1[CH:18]=O.[OH-].[K+]>>[CH3:11][O:10][C:7]1[N:8]=[CH:9][C:4]([C:1](=[O:3])/[CH:2]=[CH:18]/[C:17]2[S:16][CH:15]=[N:14][C:13]=2[CH3:12])=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 14797Potassium HydroxideHCID 5813394-Methylthiazole-5-carboxaldehydeHCID 105348375-Acetyl-2-methoxypyridine

Product 1

HCID 66667367HCID 66667367, compound

Procedure

In analogy to example 170, step 1, 5-acetyl-2-methoxypyridine was reacted with 4-methylthiazole-5-carbaldehyde in the presence of potassium hydroxide to give the title compound as an off-white solid. MS (ESI+): m/z=261.1 [M+H]+.

Sources & evidence

ORD record
ord-1142f89cebd24a658f784c1517deebe9
Source dataset
uspto-grants-2014_07
Patent number
US08765730B2

Reaction notes

Loading…