Hydroxyamine hydrochloride → HCID 58043403, compound

Participants

Reaction Steps

In analogy to example 151, step 3, 3-{4-[1-(4-chloro-2-methyl-phenyl)-3-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3-oxo-propyl]-phenoxy}-benzoic acid was reacted with hydroxylamine hydrochloride in the presence of sodium hydrogencarbonate to give the title compound containing 9% of the corresponding Z isomer as a colourless solid, MS (ESI−): m/z=515.3 [M−H]−.

Provenance & Evidence