Potassium Hydroxide → HCID 66666230, compound

HRID 1617940Notes

Reaction equation

[C:1]([C:4]1[CH:5]=[CH:6][C:7]([O:10][CH3:11])=[N:8][CH:9]=1)(=[O:3])[CH3:2].[Cl:12][C:13]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:14]=1[CH:15]=O.[OH-].[K+]>>[Cl:12][C:13]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:14]=1/[CH:15]=[CH:2]/[C:1]([C:4]1[CH:9]=[N:8][C:7]([O:10][CH3:11])=[CH:6][CH:5]=1)=[O:3]

Participants

Reactant 3

HCID 14797Potassium Hydroxide

HCID 807022,5-Dichlorobenzaldehyde

HCID 105348375-Acetyl-2-methoxypyridine

Product 1

HCID 66666230HCID 66666230, compound

Procedure

In analogy to example 170, step 1, 5-acetyl-2-methoxypyridine was reacted with 2,5-dichlorobenzaldehyde in the presence of potassium hydroxide to give the title compound as a colourless solid. MS (ESI+): m/z=308.1 [M+H]+.

Sources & evidence

ORD record: ord-3d5b175ee4734b8e957e9ca0313b45ca
Source dataset: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08765730B2

Reaction notes

Loading…