Potassium Hydroxide → HCID 66666415, compound
Reaction equation
[C:1]([C:4]1[CH:5]=[CH:6][C:7]([O:10][CH3:11])=[N:8][CH:9]=1)(=[O:3])[CH3:2].[Cl:12][C:13]1[CH:14]=[C:15]([CH:18]=[C:19]([Cl:21])[CH:20]=1)[CH:16]=O.[OH-].[K+]>>[Cl:12][C:13]1[CH:14]=[C:15](/[CH:16]=[CH:2]/[C:1]([C:4]2[CH:9]=[N:8][C:7]([O:10][CH3:11])=[CH:6][CH:5]=2)=[O:3])[CH:18]=[C:19]([Cl:21])[CH:20]=1Participants
4
Procedure
In analogy to example 170, step 1, 5-acetyl-2-methoxypyridine was reacted with 3,5-dichlorobenzaldehyde in the presence of potassium hydroxide to give the title compound as a colourless solid.
Sources & evidence
- ORD record
- ord-5f9839285d0b4d0493c64fba84196711
- Source dataset
- uspto-grants-2014_07
- Patent number
- US08765730B2
Reaction notes
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