HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → 5-fluoro-1-methyl-3-difluoromethyl-1H-pyrazole-4-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | HCID 19754735 | HCID 19754735 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | 5-fluoro-1-methyl-3-difluoromethyl-1H-pyrazole-4-carbonyl chloride | HCID 52920508 | — |
Reaction Steps
The solution of 17.8 g (100 mmol) of 5-fluoro-1-methyl-3-difluoromethyl-1H-pyrazole-4-carbaldehyde, 17.5 g (130 mmol) of sulphuryl chloride and 0.2 g of 2,2-azoisobutyronitrile in 50 ml of chlorobenzene was stirred at 80° C. for 6 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765971B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-f47a7d8be2a94effb67a669a0eb9ae73 |
| Source note | uspto-grants-2014_07 |