反应详情

温度

60 °C

To an acetic acid solution of 73 g of the thus produced product comprising 2,6-di-tert-butyl-4-acetoxymethylphenol (85.5% by GC) was added mesitylene (2.4 g) and sulfuric acid (2 g, 98%); the resulting solution was heated at 60° C. for six hours. Most of the acetic acid was removed under reduced pressure and 65-70° C.; the resulting paste was dissolved in heptane (120 g); and the resulting solution was washed with water (2×60 g) at 70-75° C. The solution was dried by azeotropic removal of water and cooled to ambient temperature; 1,3,5-trimethyl-2,4,6-tris(3,5-di-tert-butyl-4-hydroxybenzyl)benzene was isolated as an off-white solid (8.1 g).

1. customMost of the acetic acid was removed under reduced pressure and 65-70° C.
2. dissolutionthe resulting paste was dissolved in heptane (120 g)
3. washand the resulting solution was washed with water (2×60 g) at 70-75° C
4. dry with materialThe solution was dried by azeotropic removal of water
5. temperaturecooled to ambient temperature