참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Lithium Chloride | HCID 433294 | — |
| 반응물 | 1,3-Dimethyl 2-(4-bromo-2-nitrophenyl)propanedioate | HCID 15740596 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | Methyl 4-bromo-2-nitrophenylacetate | HCID 15740598 | — |
반응 단계
Prepared according to procedure H using dimethyl 2-(4-bromo-2-nitrophenyl)-malonate in DMSO (40 mL), LiCl (1.16 g, 27.4 mmol) and water (0.25 mL, 13.88 mmol) and heating at 100° C. for 15 h. After purification methyl 2-(4-bromo-2-nitrophenyl)acetate was obtained as an orange oil. Mass Spectrum (ESI) m/e=274 [(M+1) (79Br)] and 276 [(M+1) (81Br)].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08765940B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_07 |
|---|
| ORD ID | ord-9cb7fbceb0764557924f0cb8539600e3 |
|---|
| 출처 메모 | uspto-grants-2014_07 |
|---|
