HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium bis(2-methoxyethoxy)aluminiumhydride → 6-bromo-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium bis(2-methoxyethoxy)aluminiumhydride | HCID 21584525 | — |
| Reactant | 6-Bromo-3,3-dimethyl-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one | HCID 66958790 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 6-bromo-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine | HCID 67284981 | — |
Reaction Steps
Prepared according to procedure K using 6-bromo-3,3-dimethyl-1H-pyrrolo[3,2-b]pyridin-2(3H)-one (300 mg, 1.244 mmol), sodium bis(2-methoxyethoxy)-aluminium hydride (1.131 mL, 3.73 mmol) in toluene (3 mL). After purification 6-bromo-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine was obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765940B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-9777ed74a7dd43c4bca7b6b4ce060dc0 |
| Source note | uspto-grants-2014_07 |