Hydrochloric Acid → HCID 67285583, compound

Participants

Reaction Steps

1-(6-Iodo-3,3-dimethylindolin-1-yl)ethanone (6.95 g, 22.08 mmol) was combined with MeOH and concentrated HCl (25 mL, 300 mmol). The solution was heated at a gentle reflux for 1 h before it was cooled to rt. After cooling the solution to 0° C. a white solid was filtered off to give 6-iodo-3,3-dimethylindoline hydrochloride. The HCl salt was neutralized to give 6-iodo-3,3-dimethylindoline hydrochloride. Mass Spectrum (ESI) m/e=274.0 (M+1).

Provenance & Evidence