Benzene, 2-methoxy-1-methyl-4-nitro- → 3-Methoxy-4-methylaniline

Participants

Reaction Steps

Prepared according to procedure X using 2-methoxy-1-methyl-4-nitrobenzene (1.66 g, 9.9 mmol), iron powder (1.66 g, 29.8 mmol), and acetic acid (15.0 mL) to give 3-methoxy-4-methylaniline. 1H NMR (500 MHz, DMSO-d6) δ ppm 6.72 (1H, d, J=7.8 Hz), 6.18 (1H, d, J=2.0 Hz), 6.04 (1H, dd, J=7.8, 2.0 Hz), 4.81 (2H, s), 3.67 (3H, s), 1.96 (3H, s).

Provenance & Evidence