HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 4-Chloro-2-(2-fluorophenyl)-3-methylquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 178421928 | HCID 178421928 | — |
| Product | 4-Chloro-2-(2-fluorophenyl)-3-methylquinoline | HCID 59631168 | — |
Reaction Steps
Prepared according to procedure S using 2-(2-fluorophenyl)-3-methylquinolin-4-ol (0.13 g, 0.51 mmol) in POCl3 (1 mL, 10 mmol). The resulting precipitate was collected by filtration to have 4-chloro-2-(2-fluorophenyl)-3-methylquinoline. Mass Spectrum (ESI) m/e=272 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08765940B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-d193e097fb034659aa0934afa05cef08 |
| Source note | uspto-grants-2014_07 |