HuagongsheHuagongshe Chemistry Print Report · For research reference only
Anteisoheptadecanoic acid → 16-Methyloctadecanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Anteisoheptadecanoic acid | HCID 22207 | — |
| Reactant | Oxacyclotridecan-2-one | HCID 70354 | — |
| Reactant | HCID 178445864 | HCID 178445864 | — |
| Reactant | HCID 178456030 | HCID 178456030 | — |
| Product | 16-Methyloctadecanoic acid | HCID 5282601 | 84% |
Reaction Steps
16-Methyloctadecanoic acid was synthesized by the same operation, except that in the step (a) of the synthesis process for 14-methylhexadecanoic acid described above, 12-dodecanolide was changed to 15-pentadodecanolide, and in the step (b), 2-methylbutylmagnesium bromide was changed to sec-butylmagnesium bromide. Thus, 16-methyloctadecanoic add was obtained from 15-pentadodecanolide at a total yield of 84%. The purity was 95%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08771660B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-dae4c3d7677b4b24b09047547b138a85 |
| Source note | uspto-grants-2014_07 |