Cyclohexylisopropylamine → HCID 123933952, compound

HRID 1618819Notes

Reaction equation

HRID 1618819 reaction equation
[CH:1]([NH:4][CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1)([CH3:3])[CH3:2].C(N([SiH3:18])C(C)C)(C)C>>[CH:1]([N:4]([SiH3:18])[CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 62386CyclohexylisopropylamineHCID 102295364Di-iso-propylaminosilane

Product 1

HCID 123933952HCID 123933952, compoundYield 16.7%

Procedure

In a 500 ml Schlenk flask 247.3 g (1.75 mol) N-isopropylcyclohexylamine and 229.9 g (1.75 mol) di-isopropylaminosilane were refluxed for 8 days under nitrogen. The byproduct di-isopropylamine was removed with vacuum at a pressure of 40 mmHg and 50° C. Fractional vacuum distillation provided 50 g of pure N-isopropylcyclohexylaminosilane. The normal boiling point (measured at 1 atmosphere) is about 199° C. measured by differential scanning calorimetry (DSC). The end-product was characterized by mass spectroscopy (MS) which is provided in FIG. 1 with peaks at 171 (M+), 156 (M-CH3).

Workup

  1. customThe byproduct di-isopropylamine was removed with vacuum at a pressure of 40 mmHg and 50° C
  2. distillationFractional vacuum distillation

Sources & evidence

ORD record
ord-94b580ecd12f48168c52e1cda11d5a03
Source dataset
uspto-grants-2014_07
Patent number
US08771807B2

Reaction notes

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