Aniline → HCID 12170968, compound
Reaction equation
N[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:9][CH2:10][C:11]([NH-:13])=[O:12]>>[C:2]1([C:10](=[CH2:9])[C:11]([NH2:13])=[O:12])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Participants
3
Procedure
Phenyl acrylamide was synthesized via the acylation reaction of aniline followed by the β-elimination of the 3-chloropropionyl amide intermediate product (intermediate product 1).
Sources & evidence
- ORD record
- ord-0d3d2edf933449afbec762ce6d07870a
- Source dataset
- uspto-grants-2014_07
- Patent number
- US08771918B2
Reaction notes
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