HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1618890Generated: October 30, 2026
2-Tert-Butylphenol → HCID 68285452, compound
https://huagongshe.com/reaction/1618890
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Tert-Butylphenol | HCID 6923 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 3-Bromoquinoline | HCID 21413 | — |
| Reactant | 2,2,6,6-Tetramethyl-3,5-heptanedione | HCID 70700 | — |
| Catalyst | Cuprous chloride | HCID 62652 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 68285452 | HCID 68285452 | 7.1% |
Reaction Steps
0.60 g of 2-t-butylphenol, 1.3 g of cesium carbonate, 0.07 g of dipivaloylmethane, 0.42 g of 3-bromoquinoline, and 0.20 g of copper (I) chloride were dissolved in 4 ml of N-methylpyrrolidone, and the mixture was stirred for one day at 130° C. The resultant was purified by silica gel column chromatography, and 0.04 g of 3-(2-t-butyl-phenoxy)-quinoline (Compound Number 14) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08772200B2 |
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| Source dataset | uspto-grants-2014_07 |
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| ORD ID | ord-ccafe804435e49cc8591db7f63dad95d |
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| Source note | uspto-grants-2014_07 |
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