HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1618896Generated: October 31, 2026
Potassium Carbonate → HCID 68289417, compound
https://huagongshe.com/reaction/1618896
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Bromoquinoline | HCID 21413 | — |
| Reactant | 7-AMINO-2,3-DIHYDROINDEN-1-ONE | HCID 12119264 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 68289417 | HCID 68289417 | 27.8% |
Reaction Steps
0.43 g of 3-bromoquinoline, 0.29 g of 7-aminoindan-1-one, 0.08 g of copper (I) iodide, 0.41 g of potassium carbonate, and 4 ml of N-methylpyrrolidone were mixed, and then the mixture was stirred for 2 hours at 200° C. The resultant mixture was purified by silica gel column chromatography to obtain 0.15 g of 7-(quinolin-3-ylamino)-indan-1-one (Compound Number 50).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08772200B2 |
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| Source dataset | uspto-grants-2014_07 |
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| ORD ID | ord-5bbab0c577484f4a9d4d3257a1a0883c |
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| Source note | uspto-grants-2014_07 |
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