Thionyl Chloride → HCID 86663089, compound

HRID 1618917Notes

Reaction equation

HRID 1618917 reaction equation
[Cl:1][C:2]1[N:6]([CH3:7])[N:5]=[C:4]([CH:8]([F:10])[F:9])[C:3]=1[C:11]([OH:13])=O.S(Cl)([Cl:16])=O>>[Cl:1][C:2]1[N:6]([CH3:7])[N:5]=[C:4]([CH:8]([F:10])[F:9])[C:3]=1[C:11]([Cl:16])=[O:13]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 197546935-Chloro-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid

Product 1

HCID 86663089HCID 86663089, compound

Procedure

3.2 g of 5-chloro-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid and 44.3 ml of thionyl chloride were refluxed for 5 hours. After cooling down, the reaction mixture was evaporated under vacuum to yield 3.5 g of 5-chloro-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carbonyl chloride as a yellow oil.

Workup

  1. temperatureAfter cooling down
  2. customthe reaction mixture was evaporated under vacuum

Sources & evidence

ORD record
ord-a845312e60d645c18a5f4b4ea73b02b6
Source dataset
uspto-grants-2014_07
Patent number
US08772266B2

Reaction notes

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