Sodium Hydroxide → HCID 58574265, compound

Participants

Reaction Steps

The mixture of 4-bromo-2-(3-methoxypropanamido)-N-methylbenzamide (0.05 g, 0.159 mmol), 2.5 N NaOH (1 mL) and dioxane (1 mL) was stirred for 3 h at room temperature, then diluted with water, and extracted with ethyl acetate (3×10 mL). The combined organic layers were washed with brine (3×10 mL), dried over Na2SO4, filtered, and evaporated to give 59 mg of the target compound. MS (ESI): 297, 299 (MH+).

Provenance & Evidence