Hydrochloric Acid → HCID 58574452, compound

Participants

Reaction Steps

A solution of methyl 8-((3-fluorophenyl)ethynyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3 carboxylate (100 mg, 0.3 mmol, 1 equiv) in 1% NaOH (2.4 mL, 0.6 mmol, 2 equiv) and THF was stirred at room temperature overnight. Then the reaction mixture was adjusted pH to 3 with 10% aq. HCl and filtered to give 40 mg of the desired product. MS (ESI): 309 (MH+).

Provenance & Evidence