HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetaldehyde → 1-Methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetaldehyde | HCID 177 | — |
| Reactant | L-Tryptophan | HCID 6305 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 1-Methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid | HCID 73530 | 69% |
Reaction Steps
L-tryptophan (5.10 g, 25 mmol), H2SO4 (0.01 M, 30 ml) and 40% acetaldehyde (9 ml) were added in a 250 ml round-bottom flask, and then stirred and reacted at room temperature for 8 h. After filtration, wash with water and drying, white solids (4.0 g, 69%) were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772311B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-60e9dfb5241d42b3a6bfe60e4c0a460c |
| Source note | uspto-grants-2014_07 |