HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propanal → 1-Ethyl-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propanal | HCID 527 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | L-Tryptophan | HCID 6305 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-Ethyl-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid | HCID 3143288 | 74% |
Reaction Steps
L-tryptophan (5.10 g, 25 mmol), water (300 ml), H2SO4 (0.05M, 30 ml) and propionaldehyde (8 ml) were added in a 250 ml round-bottom flask, and then stirred and reacted at room temperature for 24 h. After filtration, wash with water and drying, white solids (4.5 g, 74%) were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772311B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-ca996683194049e99c65f90b7ad4bcc7 |
| Source note | uspto-grants-2014_07 |