HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 85549241, compound → HCID 73013611, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 85549241 | HCID 85549241 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 73013611 | HCID 73013611 | 99.5% |
Reaction Steps
A mixture of 0.8 g of 3-(1-tert-butoxycarbonylmethyl-6-chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)-acrylic acid ethyl ester and 80 mg of PtO2 in 60 mL of EtOAc was stirred under a balloon pressure of H2 for 1 h. The mixture was filtered through celite and concentrated to give crude product (0.8 g, white solid).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772312B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-0f2da813b1204499b542c029d99c4064 |
| Source note | uspto-grants-2014_07 |