HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86644971, compound → HCID 86644970, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86644971 | HCID 86644971 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86644970 | HCID 86644970 | 99.5% |
Reaction Steps
A mixture of 0.08 g of 3-(1-tert-butoxycarbonylmethyl-6-chloro-1H-pyrrolo[3,2-c]pyridin-2-yl)acrylic acid ethyl ester and 0.015 g of PtO2 in 12 mL of EtOAc was stirred under a balloon pressure of H2 for 16 h. The mixture was filtered through celite and concentrated to give crude product (0.08 g, white solid) MS (ESI): 367.2 (M+1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772312B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-e9a7cb3f7d6c44488da7bf804b207e15 |
| Source note | uspto-grants-2014_07 |