3-Methylbenzoic acid → 6-Bromo-2-(3-methylphenyl)benzoxazole

HRID 1619917Notes

Reaction equation

HRID 1619917 reaction equation
[Br:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[C:4]([OH:9])[CH:3]=1.[CH3:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][CH:19]=1)[C:14](O)=O>>[Br:1][C:2]1[CH:8]=[CH:7][C:5]2[N:6]=[C:10]([C:11]3[CH:12]=[C:13]([CH3:14])[CH:17]=[CH:18][CH:19]=3)[O:9][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 74183-Methylbenzoic acidHCID 143206052-Amino-5-bromophenol

Product 1

HCID 230261026-Bromo-2-(3-methylphenyl)benzoxazole

Procedure

Preparation is carried out analogously to 4.1.a from 4-bromo-2-hydroxy-aniline and 3-methyl-benzoic acid.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-1b9584a23b1948a09ea4779b5f414a89
Source dataset
uspto-grants-2014_07
Patent number
US08772323B2

Reaction notes

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