tert-Butyl piperazine-1-carboxylate → HCID 67463370, compound
Reaction equation
[Br:1][C:2]1[CH:18]=[CH:17][C:5]2[N:6]=[C:7]([C:9]3[CH:14]=[CH:13][C:12]([CH2:15]Br)=[CH:11][CH:10]=3)[O:8][C:4]=2[CH:3]=1.[N:19]1([C:25]([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26])[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[Br:1][C:2]1[CH:18]=[CH:17][C:5]2[N:6]=[C:7]([C:9]3[CH:14]=[CH:13][C:12]([CH2:15][N:22]4[CH2:21][CH2:20][N:19]([C:25]([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26])[CH2:24][CH2:23]4)=[CH:11][CH:10]=3)[O:8][C:4]=2[CH:3]=1Participants
3
Procedure
Preparation is carried out analogously to 4.1.g-2 from 6-bromo-2-(4-bromomethyl-phenyl)-benzoxazole and tert.-butyl piperazine-1-carboxylate.
Workup
- customPreparation
Sources & evidence
- ORD record
- ord-8dcbeb76331e45c88de38cbd1b3a4799
- Source dataset
- uspto-grants-2014_07
- Patent number
- US08772323B2
Reaction notes
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