5-Methylthiophene-2-carboxylic acid → HCID 23026013, compound
Reaction equation
[CH3:1][C:2]1[S:6][C:5]([C:7]([OH:9])=O)=[CH:4][CH:3]=1.[Br:10][C:11]1[CH:17]=[CH:16][C:14]([NH2:15])=[C:13](O)[CH:12]=1>>[Br:10][C:11]1[CH:17]=[CH:16][C:14]2[N:15]=[C:7]([C:5]3[S:6][C:2]([CH3:1])=[CH:3][CH:4]=3)[O:9][C:13]=2[CH:12]=1Participants
3
Procedure
Preparation is carried out analogously to 4.1.a from 5-methylthiophene-2-carboxylic acid and 4-bromo-2-hydroxy-aniline.
Workup
- customPreparation
Sources & evidence
- ORD record
- ord-34d358cb8afe4a958a13fa8202681392
- Source dataset
- uspto-grants-2014_07
- Patent number
- US08772323B2
Reaction notes
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