2-Thiophenecarboxylic acid → Methyl 2-thiophen-2-yl-benzoxazole-6-carboxylate

HRID 1619928Notes

Reaction equation

HRID 1619928 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([OH:8])=O.[NH2:9][C:10]1[CH:19]=[CH:18][C:13]([C:14]([O:16][CH3:17])=[O:15])=[CH:12][C:11]=1O>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[O:8][C:11]2[CH:12]=[C:13]([C:14]([O:16][CH3:17])=[O:15])[CH:18]=[CH:19][C:10]=2[N:9]=1

Participants

3

Reactant 2

HCID 107002-Thiophenecarboxylic acidHCID 7020619Benzoic acid, 4-amino-3-hydroxy-, methyl ester

Product 1

HCID 67466917Methyl 2-thiophen-2-yl-benzoxazole-6-carboxylate

Procedure

Preparation is carried out analogously to 4.1.a from thiophene-2-carboxylic acid and methyl 4-amino-3-hydroxybenzoate.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-b53f0c467ab94204b4c6f798c6ebd576
Source dataset
uspto-grants-2014_07
Patent number
US08772323B2

Reaction notes

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