N-methoxy-N,3-dimethylbutanamide → 3-Methyl-1-(2-phenyl-benzoxazol-6-yl)butan-1-one

HRID 1619946Notes

Reaction equation

HRID 1619946 reaction equation
Br[C:2]1[CH:16]=[CH:15][C:5]2[N:6]=[C:7]([C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=3)[O:8][C:4]=2[CH:3]=1.CON(C)[C:20](=[O:25])[CH2:21][CH:22]([CH3:24])[CH3:23]>>[CH3:23][CH:22]([CH3:24])[CH2:21][C:20]([C:2]1[CH:16]=[CH:15][C:5]2[N:6]=[C:7]([C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=3)[O:8][C:4]=2[CH:3]=1)=[O:25]

Participants

3

Reactant 2

HCID 10975620N-methoxy-N,3-dimethylbutanamideHCID 230259476-Bromo-2-phenylbenzo[d]oxazole

Product 1

HCID 674663843-Methyl-1-(2-phenyl-benzoxazol-6-yl)butan-1-one

Procedure

The preparation is carried out analogously to Example 29a from 6-bromo-2-phenyl-benzoxazole and N-methoxy-3,N-dimethyl-butyramide.

Sources & evidence

ORD record
ord-13b68ce204f54c7794668f5ec7b94f61
Source dataset
uspto-grants-2014_07
Patent number
US08772323B2

Reaction notes

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