HCID 67462533, compound → HCID 67463368, compound

Participants

Reaction Steps

9 mg (21 μmol) 5-ethyl-6-{2-[4-styryl-phenyl]-benzoxazol-6-yl}-4,5-dihydro-2H-pyridazin-3-one are hydrogenated together with 2 mg palladium on charcoal 10% and 10 ml of methanol at RT and 3.45 bar hydrogen pressure for 80 min, then the catalyst is filtered off and the filtrate is evaporated down completely i.V. The residue is purified through silica gel (eluant: DCM/methanol) and then stirred with cyclohexane/EA.

Provenance & Evidence