Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thiomorpholine | HCID 67164 | — |
| Reactant | HCID 17993492 | HCID 17993492 | — |
| Product | HCID 54591023 | HCID 54591023 | — |
Reaction Steps
A mixture of 4.1 g (0.015 mol) 5-methyl-6-(2-methylsulphanyl-benzoxazol-6-yl)-4,5-dihydro-2H-pyridazin-3-one and 10.3 g (0.1 mol) thiomorpholine is stirred for 6 h at 130° C. Then the excess thiomorpholine is eliminated by rotary evaporation in vacuo, the residue is stirred with water and diisopropylether, the crystals obtained are suction filtered. The crude product is washed with water and isopropanol and then recrystallised from aqueous isopropanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08772323B2 |
|---|
| Source dataset | uspto-grants-2014_07 |
|---|
| ORD ID | ord-f154514066c74e8499a067c2db3d468a |
|---|
| Source note | uspto-grants-2014_07 |
|---|
