Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) → HCID 67461285, compound

HRID 1619992Notes

Reaction equation

HRID 1619992 reaction equation
[Br:1][C:2]1[CH:17]=[CH:16][C:5]2[N:6]=[C:7]([C:9]3[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=3)[O:8][C:4]=2[CH:3]=1.Cl.Cl[CH2:20][CH2:21][N:22]1[CH2:27][CH2:26][O:25][CH2:24][CH2:23]1>C(#N)C>[Br:1][C:2]1[CH:17]=[CH:16][C:5]2[N:6]=[C:7]([C:9]3[CH:10]=[CH:11][C:12]([O:15][CH2:20][CH2:21][N:22]4[CH2:27][CH2:26][O:25][CH2:24][CH2:23]4)=[CH:13][CH:14]=3)[O:8][C:4]=2[CH:3]=1

Participants

4

Reactant 2

HCID 77210Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1)HCID 136409096HCID 136409096, compound

Product 1

HCID 67461285HCID 67461285, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The preparation is carried out analogously to Example 40 from 4-(6-bromo-benzoxazol-2-yl)-phenol and N-(2-chloroethyl)morpholine hydrochloride with ACN as solv.

Sources & evidence

ORD record
ord-84feb408b88c4ef0a63fe49a7219460d
Source dataset
uspto-grants-2014_07
Patent number
US08772323B2

Reaction notes

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