HCID 67467186, compound → HCID 67464448, compound

HRID 1619993Notes

Reaction equation

HRID 1619993 reaction equation
[N:1]1([CH2:7][CH2:8][O:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[O:17][C:18]4[CH:24]=[C:23](B5OC(C)(C)C(C)(C)O5)[CH:22]=[CH:21][C:19]=4[N:20]=3)=[CH:12][CH:11]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.FC(F)(F)S(O[C:40]1[CH:41]2[CH:43]([C:44](=[O:56])[N:45]([CH2:47][C:48]3[CH:53]=[CH:52][C:51]([O:54][CH3:55])=[CH:50][CH:49]=3)[N:46]=1)[CH2:42]2)(=O)=O>>[CH3:55][O:54][C:51]1[CH:50]=[CH:49][C:48]([CH2:47][N:45]2[N:46]=[C:40]([C:23]3[CH:22]=[CH:21][C:19]4[N:20]=[C:16]([C:13]5[CH:14]=[CH:15][C:10]([O:9][CH2:8][CH2:7][N:1]6[CH2:6][CH2:5][O:4][CH2:3][CH2:2]6)=[CH:11][CH:12]=5)[O:17][C:18]=4[CH:24]=3)[CH:41]3[CH:43]([CH2:42]3)[C:44]2=[O:56])=[CH:53][CH:52]=1

Participants

3

Reactant 2

HCID 67467186HCID 67467186, compoundHCID 86689071HCID 86689071, compound

Product 1

HCID 67464448HCID 67464448, compound

Procedure

The preparation is carried out analogously to Example 136c from 2-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoxazole and 4-(4-methoxy-benzyl)-5-oxo-3,4-diaza-bicyclo[4.1.0]hept-2-en-2-yl trifluoromethanesulphonate.

Sources & evidence

ORD record
ord-65d9802f44db41a9b93802fb49dd132b
Source dataset
uspto-grants-2014_07
Patent number
US08772323B2

Reaction notes

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