HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1620388Generated: November 1, 2026
Hydrochloric Acid → methyl(S)-3-amino-2-morpholin-4-ylpropanoate hydrochloride
https://huagongshe.com/reaction/1620388
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | methyl(S)-3-tert-butoxycarbonylamino-2-morpholin-4-ylpropanoate | HCID 67056346 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | methyl(S)-3-amino-2-morpholin-4-ylpropanoate hydrochloride | HCID 67495365 | 96% |
Reaction Steps
A solution of 1.4 g (5 mmol) of methyl(S)-3-tert-butoxycarbonylamino-2-morpholin-4-ylpropanoate in 20 ml of methanol and 10 ml of a solution of hydrochloric acid having a 5-6N concentration in isopropanol is stirred at 40° C. for 20 h and then evaporated to dryness. 1.3 g (96%) of methyl(S)-3-amino-2-morpholin-4-ylpropanoate hydrochloride are obtained in the form of a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08772478B2 |
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| Source dataset | uspto-grants-2014_07 |
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| ORD ID | ord-ceae3ab955bb427a8ed948687938eb6c |
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| Source note | uspto-grants-2014_07 |
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