N,N-Diethylethylenediamine → HCID 178464053, compound

HRID 1620475Notes

Reaction equation

HRID 1620475 reaction equation
S=[C:2]1[CH2:6][S:5][C:4](=[O:7])[NH:3]1.[CH2:8]([N:10]([CH2:14][CH3:15])[CH2:11][CH2:12][NH2:13])[CH3:9]>CO>[CH2:8]([N:10]([CH2:14][CH3:15])[CH2:11][CH2:12][NH:13][C:2]1[CH2:6][S:5][C:4](=[O:7])[N:3]=1)[CH3:9]

Participants

4

Reactant 2

HCID 60993N,N-DiethylethylenediamineHCID 15395954-Sulfanylidene-1,3-thiazolidin-2-one

Product 1

HCID 178464053HCID 178464053, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 4-thioxo-1,3-thiazolidin-2-one (5.32 g) in methanol (200 mL) was added N,N-diethylethane-1,2-diamine (6.17 mL). The reaction mixture was stirred at room temperature overnight, and the solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (NH, ethyl acetate/hexane) to give the title compound (5.44 g).

Workup

  1. customthe solvent was evaporated under reduced pressure
  2. customThe residue was purified by silica gel column chromatography (NH, ethyl acetate/hexane)

Sources & evidence

ORD record
ord-643f229b7a2c4b8ea85defa188b7b6d0
Source dataset
uspto-grants-2014_07
Patent number
US08772277B2

Reaction notes

Loading…