2-Propanol, 1-amino-2-methyl- → HCID 178459301, compound

HRID 1620513Notes

Reaction equation

HRID 1620513 reaction equation
[NH2:1][CH2:2][C:3]([CH3:6])([OH:5])[CH3:4].S=[C:8]1[CH2:12][S:11][C:10](=[O:13])[NH:9]1>C(O)C>[OH:5][C:3]([CH3:6])([CH3:4])[CH2:2][NH:1][C:8]1[CH2:12][S:11][C:10](=[O:13])[N:9]=1

Participants

4

Reactant 2

HCID 951022-Propanol, 1-amino-2-methyl-HCID 15395954-Sulfanylidene-1,3-thiazolidin-2-one

Product 1

HCID 178459301HCID 178459301, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 1-amino-2-methylpropan-2-ol (2.61 g) in ethanol (30 mL) was added 4-thioxo-1,3-thiazolidin-2-one (3 g), and the mixture was stirred at room temperature for 6 hr. The reaction mixture was concentrated, and the residue was washed with ethanol to give the title compound (3.90 g).

Workup

  1. concentrationThe reaction mixture was concentrated
  2. washthe residue was washed with ethanol

Sources & evidence

ORD record
ord-288b69e3233e4c75994160fe849bd669
Source dataset
uspto-grants-2014_07
Patent number
US08772277B2

Reaction notes

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