[4-(4-Amino-2-fluoro-phenoxy)-6,7-dimethoxy-quinolin-2-yl]-methyl-amine → N-(3-fluoro-4-{[2-(methylamino)-6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Reaction equation
[CH3:26][O:27][c:28]1[cH:29][c:30]2[c:31]([cH:32][c:33]1[O:34][CH3:35])[n:36][c:37]([S:38][CH3:39])[cH:40][c:41]2[O:42][c:43]1[cH:44][cH:45][c:46]([NH:47][C:50](=[O:51])[C:52]2([C:55](=[O:56])[NH:57][c:58]3[cH:59][cH:60][c:61]([F:64])[cH:62][cH:63]3)[CH2:53][CH2:54]2)[cH:48][c:49]1[F:65].[NH2:1][c:2]1[cH:3][c:4]([F:25])[c:5]([O:6][c:7]2[cH:8][c:9]([NH:21][CH3:22])[n:10][c:11]3[cH:12][c:13]([O:19][CH3:20])[c:14]([O:17][CH3:18])[cH:15][c:16]23)[cH:23][cH:24]1>>[NH:1]([c:2]1[cH:3][c:4]([F:25])[c:5]([O:6][c:7]2[cH:8][c:9]([NH:21][CH3:22])[n:10][c:11]3[cH:12][c:13]([O:19][CH3:20])[c:14]([O:17][CH3:18])[cH:15][c:16]23)[cH:23][cH:24]1)[C:50](=[O:51])[C:52]1([C:55](=[O:56])[NH:57][c:58]2[cH:59][cH:60][c:61]([F:64])[cH:62][cH:63]2)[CH2:53][CH2:54]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-c1e0ea70a07849fe8741bc4f29628930
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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