反应详情

A solution of ethyl 4-({[(4-methylphenyl)sulfonyl]oxy}imino)cyclohexanecarboxylate (22.0 g) in acetic acid (150 mL) was stirred at room temperature for 1 hr, and the reaction mixture was concentrated under reduced pressure. Saturated aqueous sodium hydrogen carbonate solution was added, and the mixture was extracted with ethyl acetate. The extract was dried over anhydrous sodium sulfate, and the solvent was evaporated under reduced pressure to give the title compound (8.62 g).

1. concentrationthe reaction mixture was concentrated under reduced pressure
2. additionSaturated aqueous sodium hydrogen carbonate solution was added
3. extractionthe mixture was extracted with ethyl acetate
4. dry with materialThe extract was dried over anhydrous sodium sulfate
5. customthe solvent was evaporated under reduced pressure