4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178484587, compound

Participants

Reaction Steps

To a solution of N,N-dimethyl-D-serinamide (645 mg) in ethanol (20 mL) was added 4-thioxo-1,3-thiazolidin-2-one (650 mg), and the mixture was heated under reflux overnight. The reaction mixture was concentrated under reduced pressure, the residue was purified by silica gel column chromatography (NH, methanol/ethyl acetate), and the obtained powder was washed with ethyl acetate to give the title compound (799 mg).

Provenance & Evidence